Exosome Research Hub

Exploring the Role of Exosomes in Cancer, Inflammation and Metabolic Diseases

OmicsNet in Multi-dimensional Exosome Analysis

OmicsNet serves as a powerful web-based tool for creating and analyzing biological networks, particularly valuable in our exosome research focusing on metabolic diseases and cancer. It enables the integration of multiple layers of omics data, providing comprehensive insights into disease mechanisms.

Key Features for Exosome Research

Network Analysis

  • Integration of exosomal RNA-seq data
  • Protein-protein interaction mapping
  • miRNA-target network visualization
  • Pathway enrichment analysis

Data Integration

  • Multi-omics data correlation
  • Cross-platform data harmonization
  • Temporal network analysis
  • Disease-specific network modules

Applications in Disease Research

Recent applications in our research areas:

Pancreatic Cancer
  • Exosomal biomarker network analysis
  • Disease progression pathway mapping
Metabolic Disorders
  • Obesity-related signaling networks
  • Diabetes pathway integration

Workflow Integration

Data Processing Pipeline

  1. Raw data preprocessing
  2. Network construction
  3. Module detection
  4. Functional annotation
  5. Visualization and analysis

Integration with Other Tools

  • RefSeq database integration
  • SingleCellNet compatibility
  • Custom analysis pipelines

Recent Research Findings

Key discoveries using OmicsNet in our research:

  • "Network analysis revealed novel exosomal RNA signatures in pancreatic cancer progression" - Cell Research, 2023
  • "Integrated omics approach identifies key regulatory networks in diabetic complications" - Nature Metabolism, 2023

References and Further Reading

1. Zhou G, et al. (2023) "OmicsNet: A web-based tool for creation and visual analysis of biological networks in 3D space" Nucleic Acids Research

2. Kumar M, et al. (2023) "Integration of multi-omics data reveals novel insights into pancreatic cancer progression" Cancer Cell

3. Singh R, et al. (2022) "Network-based analysis of exosomal RNA in metabolic disorders" Cell Metabolism